Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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646
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646
Tocris Bioscience™ Phalloidin-TRITC
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Red-orange fluorescent cytoskeleton stain
647
Tocris Bioscience™ O-Propargyl-puromycin
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Puromycin analog for labeling newly synthesized proteins; is incorporated into nascent polypeptides
648
Tocris Bioscience™ SJF 0661
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Negative control for SJF 0628 (Cat. No. 7463)
650
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Thermo Scientific Chemicals Venlafaxine hydrochloride
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Thermo Scientific Chemicals Venlafaxine hydrochloride
CAS: 99300-78-4 Molecular Formula: C17H27NO2·HCl
| CAS | 99300-78-4 |
|---|---|
| Molecular Formula | C17H27NO2·HCl |
651
Tocris Bioscience™ CELT-211
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Fluorescent serotonin 5HT2B receptor ligand for HTS
652
Tocris Bioscience™ 1M7
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Reagent for RNA SHAPE-MaP chemistry
654
Tocris Bioscience™ DR 4485 Hydrochloride
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High affinity and selective 5-HT7 antagonist; orally bioavailable
| CAS | 402942-53-4 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | 6-Chloro-2a-[4-[4-(4-chlorophenyl)-3,6-dihydro-1(2H)-pyridinyl]butyl]-2a,3,4,5-tetrahydrobenz[cd]indol-2(1H)-one hydrochloride |
| Recommended Storage | Desiccate at Room Temperature |
| Molecular Formula | C26H28Cl2N2O.HCl |
| Formula Weight | 491.88 |
655
Tocris Bioscience™ Ethyl LipotF
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective FTO inhibitor
656
Tocris Bioscience™ LP 99
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Selective BRD7 and BRD9 inhibitor (Kd values are 99 and 909 nM, respectively)
| CAS | 1808951-93-0 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | N-[(2R,3S)-2-(4-Chlorophenyl)-1-(1,2-dihydro-1,4-dimethyl-2-oxo-7-quinolinyl)-6-oxo-3-piperidinyl]-2-methyl-1-propanesulfonamide |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C26H30ClN3O4S |
| Formula Weight | 516.05 |
657
Tocris Bioscience™ AMG 900
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Potent pan-Aurora kinase inhibitor
| Target | Aurora Kinase Inhibitors |
|---|---|
| CAS | 945595-80-2 |
| Purity | 98% |
| Chemical Name or Material | N-[4-[[3-(2-Amino-4-pyrimidinyl)-2-pyridinyl]oxy]phenyl]-4-(4-methyl-2-thienyl)-1-phthalazinamine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C28H21N7OS |
658
Tocris Bioscience™ eIF4A i28
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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eIF4A inhibitor
659
Tocris Bioscience™ SLM 6031434 hydrochloride
Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Greener Choice
Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”
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Small and Specialty Supplier Partner
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Selective sphingosine kinase 2 (Sphk2) inhibitor
| CAS | 1897379-34-8 |
|---|---|
| Purity | 98% |
| Chemical Name or Material | (2S)-2-[3-[4-(Octyloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl]-1-pyrrolidinecarboximidamide hydrochloride |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C22H30F3N5O2.HCl |
660
MilliporeSigma™ Calbiochem™ Mitochondrial GPDH Inhibitor, iGP-1
A cell-permeable, potent, selective, and dose-dependent inhibitor of mitochondrial, but not cytosolic, sn-glycerol-3-phosphate dehydrogenase (IC50 against mGPDH = 6.3 μM).